The dominating Real Madrid fell in defeat, Zinedine Zidane suffered from a shoulder dislocation, and a referee was injured during a match.
The opening of the UEFA Championship league on September 16 ended with a surprise defeat for Real Madrid, injuries for players, and an attack on a referee during a match.
The first Group B match was between Germanys Leverkusen and Spains Real Madrid.
Leverkusens Jacek Krzynowek, Franca, and Dimitar Berbatovs goals were enough to consign the almighty Real Madrids Ronaldo, Zidane, Beckham, and Figo to a 3-0 defeat.
The victory by Leverkusen over Real Madrid was its first after a sluggish one-tie and four-loss record.
Zidane, one of Reals key midfielders, suffered from a shoulder dislocation in the beginning of the second half and will not be able to play for the next three weeks.
During the match between Italys AS Roma and the Ukraines Dynamo Kiev, a projectile thrown by a fan hit the referee.
Minutes before the end of the first half, the Swedish referee Anders Frisk ejected AS Romas Philippe Mexes from the game. Moments later, a projectile assumed to be a lighter flew from that stands and hit Frisk on his forehead. The match was suspended while Kiev was leading 1-0, and the UEFA disciplinary committee will soon decide the penalties to be handed out to AS Roma.